Does beta-alanine activate more than one chloride channel associated receptor?

@article{Choquet1988DoesBA,
  title={Does beta-alanine activate more than one chloride channel associated receptor?},
  author={Daniel Choquet and Henri Korn},
  journal={Neuroscience letters},
  year={1988},
  volume={84 3},
  pages={329-34}
}
In order to define which receptor-channel complexes are activated by beta-alanine, we performed cross-desensitization experiments between this amino acid and the classical inhibitory neurotransmitters, glycine and gamma-aminobutyric acid (GABA), all of which increase chloride conductances. Using the whole-cell patch-clamp technique and cultured chick spinal neurons, we found that beta-alanine completely desensitizes the glycine response, and only partially reduces GABA evoked currents. No… CONTINUE READING