Does antipsychotic withdrawal provoke psychosis? Review of the literature on rapid onset psychosis (supersensitivity psychosis) and withdrawal‐related relapse

@article{Moncrieff2006DoesAW,
  title={Does antipsychotic withdrawal provoke psychosis? Review of the literature on rapid onset psychosis (supersensitivity psychosis) and withdrawal‐related relapse},
  author={J. Moncrieff},
  journal={Acta Psychiatrica Scandinavica},
  year={2006},
  volume={114}
}
  • J. Moncrieff
  • Published 2006
  • Psychology, Medicine
  • Acta Psychiatrica Scandinavica
Objective:  To examine the evidence that discontinuation of long‐term antipsychotic medication, including clozapine, may provoke a psychotic episode. 
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The following case report is the first time that this phenomenon has been described in an adolescent patient who has discontinued ziprasidone and reasons for supersensitivity psychosis are explored. Expand
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References

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: The authors present a case of neuroleptic-induced supersensitivity psychosis in a manic-depressive patient. They discuss the clinical differentiation of such a withdrawal psychosis from… Expand
Psychosis after neuroleptic withdrawal in a manic-depressive patient.
The authors present a case of neuroleptic-induced supersensitivity psychosis in a manic-depressive patient. They discuss the clinical differentiation of such a withdrawal psychosis from schizophrenic… Expand
Supersensitivity psychosis in schizophrenic patients after sudden clozapine withdrawal
In two patients with chronic schizophrenia, who were on clozapine medication for more than 6 months, a sudden withdrawal of the drug resulted in a very pronounced deterioration of the psychosis… Expand
Rebound psychosis: Effect of discontinuation of antipsychotics in Parkinson's disease
To determine whether psychiatrically stable patients with a history of drug‐induced psychosis could be successfully weaned off their antipsychotic drug, we offered consecutive Parkinson disease (PD)… Expand
The consequences of suddenly stopping psychotropic medication in bipolar disorder
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This review explores current understanding of the effects of psychotropic discontinuation in bipolar disorder with a focus on the discontinuation effects of lithium. Expand
Neuroleptic‐induced supersensitivity psychosis in patients with bipolar affective disorder
TLDR
The authors present 5 cases of supersensitivity psychosis that developed in patients with bipolar affective disorder and the implications for the long‐term course of bipolar Affective disorder are discussed. Expand
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TLDR
The authors' pilot data do not seem to support the existence of supersensitivity psychosis, as the sudden worsening of psychotic symptoms and tardive dyskinesia postulated in the SSP group was not observed on the Brief Psychiatric Rating Scale, the Clinical Global Impressions scale, and the Abbreviated Dyskine Rating Scale. Expand
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TLDR
The case of a 34 year old woman is presented, in whom the return of psychotic symptoms following the discontinuation of neuroleptic medications is attributed to a rebound phenomena as opposed to a relapse of an underlying chronic illness. Expand
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TLDR
Using Chouinard's criteria, the authors found 12 probable but no definitive cases of this syndrome while conducting a chart review of 265 hospitalized schizophrenic patients, and six of the 12 patients were subsequently rediagnosed as schizoaffective. Expand
Rebound psychoses following the discontinuation of a high potency neuroleptic.
  • G. J. Kahne
  • Medicine
  • Canadian journal of psychiatry. Revue canadienne de psychiatrie
  • 1989
TLDR
The case of a 34 year old woman is presented, in whom the return of psychotic symptoms following the discontinuation of neuroleptic medications is attributed to a rebound phenomena as opposed to a relapse of an underlying chronic illness. Expand
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