Does anti-oxidant prophylaxis with melatonin prevent adverse outcomes related to increased oxidative stress caused by laparoscopy in experimental rat model?

@article{ay2006DoesAP,
  title={Does anti-oxidant prophylaxis with melatonin prevent adverse outcomes related to increased oxidative stress caused by laparoscopy in experimental rat model?},
  author={Ali Çay and Mustafa Imamoğlu and Mesut A. Unsal and S. Han Aydin and Ahmet Alver and Ahmet Akyol and Haluk Sarihan},
  journal={The Journal of surgical research},
  year={2006},
  volume={135 1},
  pages={2-8}
}
BACKGROUND We hypothesized that prophylaxis with an anti-oxidant should prevent potential adverse outcomes of laparoscopy related to increased oxidative stress in splanchnic organs, including small intestine, liver, and kidneys, and melatonin is the most appropriate agent for this purpose. METHODS Twenty-four Sprague-Dawley rats weighing 300 to 350 g were… CONTINUE READING