Does an increase in serum creatinine always reflect renal injury? The case of Stribild®

@article{Arya2013DoesAI,
  title={Does an increase in serum creatinine always reflect renal injury? The case of Stribild®},
  author={Vikram Arya and Jeffry A Florian and Kendall A Marcus and Kellie Schoolar Reynolds and Linda L. Lewis and Adam I Sherwat},
  journal={Journal of clinical pharmacology},
  year={2013}
}
Single tablet, once-daily HIV treatment regimens offer patient convenience, the potential for increased adherence, and fewer patient-related dosing errors[1] . Stribild® (manufactured and marketed by Gilead Sciences; referred to as "applicant" in this report), a 4-drug fixed-dose combination (FDC) tablet, is approved for the treatment of HIV-1 infection in treatment-naïve adult patients. Stribild® contains elvitegravir (an integrase strand transfer inhibitor), cobicistat (an inhibitor of… CONTINUE READING