Does age affect gastric emptying time? A model‐based meta‐analysis of data from premature neonates through to adults

@inproceedings{Bonner2015DoesAA,
  title={Does age affect gastric emptying time? A model‐based meta‐analysis of data from premature neonates through to adults},
  author={Jennifer J. Bonner and Pavan Vajjah and Khaled Abduljalil and Mohammad Masjed Jamei and Amin Rostami‐Hodjegan and Geoffrey T. Tucker and Trevor N. Johnson},
  booktitle={Biopharmaceutics & drug disposition},
  year={2015}
}
PURPOSE Gastric emptying (GE) is often reported to be slower and more irregular in premature neonates than in older children and adults. The aim of this study was to investigate the impact of age and other covariates on the rate of GE. METHODS The effect of age on the mean gastric residence times (MGRT) of liquid and solid food was assessed by analysing 49 published studies of 1457 individuals, aged from 28 weeks gestation to adults. The data were modelled using the nonlinear mixed-effects… CONTINUE READING
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