Does actin bind to the ends of thin filaments in skeletal muscle?

@article{Ishiwata1985DoesAB,
  title={Does actin bind to the ends of thin filaments in skeletal muscle?},
  author={Shin'ichi Ishiwata and Takashi Funatsu},
  journal={The Journal of Cell Biology},
  year={1985},
  volume={100},
  pages={282 - 291}
}
We examined whether or not purified actin binds to the ends of thin filaments in rabbit skeletal myofibrils. Phase-contrast, fluorescence, and electron microscopic observations revealed that actin does not bind to the ends of thin filaments of intact myofibrils. However, in I-Z-I brushes prepared by dissolving thick filaments at high ionic strength, marked… CONTINUE READING