Does a polymorphic glucocorticoid receptor explain inherited altered stress response and increased anxiety-type behaviors in a mouse population?

Abstract

Xu et al. reported in The FASEB Journal on a selection study in mice allegedly implicating a polymorphic glucocorticoid receptor (GR) in inherited altered stress response and increased anxiety-type behaviors (1). Xu et al. carried out “divergent genetic selection for altered corticosterone response to stress” and found that the resulting two lines differed… (More)
DOI: 10.1096/fj.08-0102LTR

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