Does Physiological Blood Glucose Control Require an Adaptive Control Strategy?

  title={Does Physiological Blood Glucose Control Require an Adaptive Control Strategy?},
  author={Uwe Fischer and Wolfgang Schenk and E. Salzsieder and G{\"u}nther Albrecht and Phillip Abel and E. -J. Freyse},
  journal={IEEE Transactions on Biomedical Engineering},
To test the hypothesis that only an adaptive algorithm would guarantee optimal feedback control of glycemia in insulin-dependent diabetes, fasting chronically diabetic dogs at rest were subjected to short-term artificial beta cell treatment. Insulin was applied intravenously and an oral glucose load was given during the experiment. Employing the same dosing algorithm, three different control strategies were employed in a random order on different days: adaptive control (minimum variance… CONTINUE READING
23 Citations
26 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 23 extracted citations


Publications referenced by this paper.
Showing 1-10 of 26 references

, " Computerassisted continuous infusion of the intravenous analgesic fentanyl during general anesthesiaAn interactive system

  • J. M. Alvis, J. G. Reves, L. C. Sheppard
  • Biomed . Eng .
  • 1985

Cukerman , " Intermittent hyperinsulinaemia and arterial glycosaminoglycans in dogs

  • A. Sirek V. Sirek, E.
  • 1985

Chipps , " A semi - closed loop computer - assisted insulin infusion system

  • E. W. Kraegen D. J. Chisholm, D. J. Bell, R. D.
  • Med . J . Austr .
  • 1984

Similar Papers

Loading similar papers…