Does MDS with der(1;7)(q10;p10) constitute a distinct risk group? A retrospective single institutional analysis of clinical/pathologic features compared to -7/del(7q) MDS.

Abstract

The der(1;7)(q10;p10) aberration is observed in about 1-3% of the myelodysplastic syndromes (MDS) and less commonly in acute myeloid leukemia (AML) and the myeloproliferative disorders. This unbalanced translocation is considered a "variant" of the del(7q)/-7 subgroup and has been assigned a poor risk karyotype score in the MDS International Prognostic… (More)
DOI: 10.1016/j.cancergencyto.2009.04.013

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@article{Slovak2009DoesMW, title={Does MDS with der(1;7)(q10;p10) constitute a distinct risk group? A retrospective single institutional analysis of clinical/pathologic features compared to -7/del(7q) MDS.}, author={Marilyn L. Slovak and Margaret O'donnell and D. Alastair Smith and Karl K. Gaal}, journal={Cancer genetics and cytogenetics}, year={2009}, volume={193 2}, pages={78-85} }