Does Hypoxia Cause Carcinogenic Iron Accumulation in Alcoholic Liver Disease (ALD)?

@inproceedings{Silva2017DoesHC,
  title={Does Hypoxia Cause Carcinogenic Iron Accumulation in Alcoholic Liver Disease (ALD)?},
  author={In{\^e}s Milagre da Silva and Vanessa Rausch and Helmut-Karl Seitz and Sebastian B Mueller},
  booktitle={Cancers},
  year={2017}
}
Alcoholic liver disease (ALD) is a leading health risk worldwide. Hepatic iron overload is frequently observed in ALD patients and it is an important and independent factor for disease progression, survival, and the development of primary liver cancer (HCC). At a systemic level, iron homeostasis is controlled by the liver-secreted hormone hepcidin. Hepcidin regulation is complex and still not completely understood. It is modulated by many pathophysiological conditions associated with ALD, such… CONTINUE READING
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