Does Hyaluronic Acid Distribution in the Larynx Relate to the Newborn's Capacity for Crying?

@article{Schweinfurth2008DoesHA,
  title={Does Hyaluronic Acid Distribution in the Larynx Relate to the Newborn's Capacity for Crying?},
  author={John M Schweinfurth and Susan L. Thibeault},
  journal={The Laryngoscope},
  year={2008},
  volume={118}
}
Objectives/Hypothesis: The newborn is heavily dependent on voice communication and therefore has relatively higher vocal demands and expenditures than the adult, the loudness output per mass performance exceeds that of the adult, and the newborn larynx exhibits significant histological and biochemical differences. The neonatal larynx is capable of sustaining relatively greater pitch and loudness than the adult over longer periods of time. This ability may be related to a more compact… 
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References

SHOWING 1-10 OF 57 REFERENCES
Age-Related Development of the Arrangement of Connective Tissue Fibers in the Lamina Propria of the Human Vocal Fold
TLDR
The development of the layered structure and the maturity of the fibers appeared to reflect the complexity of phonatory function during adolescence, and the structure of the lamina propria was complete around 17 years of age.
Fine Structure of the Human Newborn and Infant Vocal Fold Mucosae
TLDR
During infancy, the extracellular matrices synthesized in the maculae flavae appear in the membranous portion of the vocal fold, each at a different time, so as to initiate the 3-dimensional formation ofThe vocal fold mucosa.
The intermediate layer: a morphologic study of the elastin and hyaluronic acid constituents of normal human vocal folds.
TLDR
The morphologic features of elastin and hyaluronic acid, two important constituents of the lamina propria, were evaluated and it was found that theElastin composition of the vocal folds is variable, the largest amount being seen in the midportion on Elastin-van Gieson (EVG) staining and ultrastructural evaluation.
Age- and gender-related elastin distribution changes in human vocal folds
TLDR
There was an increase in elastin content from the infant through geriatric stages and the distributions were consistent with previous observations that the lamina propria is a layered structure with most of theElastin present in the intermediate layer.
Quantitative and Comparative Studies of the Vocal Fold Extracellular Matrix I: Elastic Fibers and Hyaluronic Acid
TLDR
The elastin content of the human LP is roughly twice that of the dermis, whereas the HAcontent of thehuman LP is similar to that ofThe dermis.
The importance of hyaluronic acid in vocal fold biomechanics.
  • R. Chan, S. Gray, I. Titze
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2001
TLDR
The results suggested that such clinical use as a potential bioimplant for the surgical repair of vocal fold ECM defects may be potentially optimal for voice production from a biomechanical perspective.
Expression and Distribution of CD44 and Hyaluronic Acid in Human Vocal Fold Mucosa
TLDR
Stellate cells in the macula flava and CD44 cooperatively play important roles in maintaining hyaluronic acid in the human vocal fold mucosa as a vibrating tissue.
Vocal fold proteoglycans and their influence on biomechanics
TLDR
Proteoglycans, particularly hyaluronic acid, play important roles in determining biomechanical properties of tissue oscillation and future research will likely make these proteins of important therapeutic interest.
A Study of Age- and Gender-related Elastin Distribution Changes in Human Vocal Folds
tive contribution of specific variables is not well described. To evaluate the modulation of fundamental frequency (pitch) in tracheoesophageal (TE) speakers following total laryngectomy and voice
Functions of hyaluronan.
TLDR
The structure, physical chemical properties and biology of hyaluronan have been frequently reviewed and the reader is referred to these articles.
...
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5
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