Does Glycosylation as a modifier of Original Antigenic Sin explain the case age distribution and unusual toxicity in pandemic novel H1N1 influenza?

@inproceedings{Reichert2010DoesGA,
  title={Does Glycosylation as a modifier of Original Antigenic Sin explain the case age distribution and unusual toxicity in pandemic novel H1N1 influenza?},
  author={Thomas A Reichert and Gerardo Chowell and Hiroshi Nishiura and Ronald A Christensen and Jonathan A. McCullers},
  booktitle={BMC infectious diseases},
  year={2010}
}
BACKGROUND A pandemic novel H1N1 swine-origin influenza virus has emerged. Most recently the World Health Organization has announced that in a country-dependent fashion, up to 15% of cases may require hospitalization, often including respiratory support. It is now clear that healthy children and young adults are disproportionately affected, most unusually among those with severe respiratory disease without underlying conditions. One possible explanation for this case age distribution is the… CONTINUE READING