Does Dextrose Affect Analgesia or the Side Effects of Intrathecal Sufentanil?

@article{Gage1997DoesDA,
  title={Does Dextrose Affect Analgesia or the Side Effects of Intrathecal Sufentanil?},
  author={J. Gage and R. D’angelo and R. Miller and J. Eisenach},
  journal={Anesthesia \& Analgesia},
  year={1997},
  volume={85},
  pages={826-830.}
}
Intrathecal (IT) sufentanil provides rapid effective pain relief for early labor, but it also produces undesirable side effects, which may be primarily related to cephalad spread.Although the combination of dextrose and positioning the patient head-up limits the spread of other spinally administered drugs, these factors have not been examined in laboring women receiving IT sufentanil. We hypothesized that the addition of dextrose to IT sufentanil injected with women in the sitting position… Expand
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The addition of dextrose 3.5% to intrathecal sufentanil reduced the incidence of pruritus without affecting the duration or quality of analgesia in parturients in early labour. Expand
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Low-dose clonidine and neostigmine prolong the duration of intrathecal bupivacaine-fentanyl for labor analgesia.
TLDR
The addition of clonidine and neostIGmine significantly increased the duration of analgesia from IT bupivacaine-fentanyl during labor, but neostigmine caused more nausea. Expand
Intrathecal Clonidine for Postoperative Analgesia in Elderly Patients: The Influence of Baricity on Hemodynamic and Analgesic Effects
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TLDR
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Hyperbaric Bupivacaine 2.5 mg Prolongs Analgesia Compared with Plain Bupivacaine When Added to Intrathecal Fentanyl 25 &mgr;g in Advanced Labor
TLDR
Under these circumstances, hyperbaric bupvacaine conferred an increased duration of IT analgesia compared with plain bupivacaine. Expand
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TLDR
Posture during IT injection of this dextrose-free analgesic combination affects extent of sensory block in laboring parturients, and those in a sitting position during IT injections had significantly higher maximal cephalad extent of block. Expand
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The rapid onset of analgesia and lack of motor blockade from intrathecal sufentanil injection may be advantageous in certain clinical situations, however, pruritus is common; hypotension may occur; and extensive dermatomal spread suggests that early-onset respiratory depression could occur. Expand
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TLDR
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TLDR
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