Does Cocaine Still Have a Role in Nasal Surgery?

@article{Latorre1999DoesCS,
  title={Does Cocaine Still Have a Role in Nasal Surgery?},
  author={F. Latorre and L. Klimek},
  journal={Drug Safety},
  year={1999},
  volume={20},
  pages={9-13}
}
Endonasal surgery is already very common and its importance is increasing. Successful anaesthesia in endonasal sinus surgery is of critical importance for the success of the procedure and many surgeons prefer to use cocaine for this purpose. However, there is a great body of evidence that suggests that use of cocaine, even in experienced hands, can cause rapid, unexpected and severe toxic reactions. Therefore, its use in endonasal surgery can no longer be recommended, especially since better… Expand
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  • Medicine
  • The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique
  • 2006
TLDR
Iatrogenic cocaine toxicity was observed in a 5-month-old male who received intranasal cocaine as a topical anesthetic for laryngoscopy and required 3 doses of IV lorazepam. Expand
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  • 2014
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Effects of Remifentanil on Hemodynamic Responses of Exogeneous Epinephrine during Endoscopic Sinus Surgery
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