Does Alkaline Colonic pH Predispose to Clostridium difficile Infection?

  title={Does Alkaline Colonic pH Predispose to Clostridium difficile Infection?},
  author={Purba Gupta and Stanley Yakubov and Kevin Tin and Diego Zea and Olga Garankina and Monica Ghitan and Edward K. Chapnick and Peter Homel and Yu Shia Lin and Michael M Koegel},
  journal={Southern medical journal},
  volume={109 2},
OBJECTIVES Clostridium difficile caused nearly 500,000 infections and was associated with approximately 29,000 deaths in 2011, according to data from the Centers for Disease Control and Prevention. C. difficile is a bacterium that causes diarrhea and, often, severe illness in healthcare facilities, as well as the community. Our objective was to determine whether alkaline colonic pH predisposes to colonization and infection with C. difficile. METHODS A total of 228 patients with diarrhea and… CONTINUE READING
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