Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine.

@article{Bell2002Does5R,
  title={Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine.},
  author={Caroline J. Bell and Sam W Forshall and Mariona Adrover and Jon R. Nash and Sean David Hood and Spilios V. Argyropoulos and Ann S. Rich and David J. Nutt},
  journal={Journal of psychopharmacology},
  year={2002},
  volume={16 1},
  pages={5-14}
}
The neurobiological basis of panic disorder has not been clearly established, although a role for serotonin (5-HT) has been postulated. It is clear that drugs which increase 5-HT neurotransmission are effective in treating the condition but how they do so remains a point of debate. The aim of this study was to determine if lowering brain serotonin activity using the technique of tryptophan depletion provoked a short-term relapse of panic symptoms in patients with panic disorder who had… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

Similar Papers

Loading similar papers…