Dodecafluoropentane emulsion decreases infarct volume in a rabbit ischemic stroke model.

@article{Culp2012DodecafluoropentaneED,
  title={Dodecafluoropentane emulsion decreases infarct volume in a rabbit ischemic stroke model.},
  author={William C. Culp and Sean Woods and Robert D. Skinner and Aliza Brown and John D Lowery and Jennifer L H Johnson and Evan C. Unger and Leah Hennings and Michael J. Borrelli and Paula K Roberson},
  journal={Journal of vascular and interventional radiology : JVIR},
  year={2012},
  volume={23 1},
  pages={116-21}
}
PURPOSE To assess the efficacy of dodecafluoropentane emulsion (DDFPe), a nanodroplet emulsion with significant oxygen transport potential, in decreasing infarct volume in an insoluble-emboli rabbit stroke model. MATERIALS AND METHODS New Zealand White rabbits (N = 64; weight, 5.1 ± 0.50 kg) underwent angiography and received embolic spheres in occluded internal carotid artery branches. Rabbits were randomly assigned to groups in 4-hour and 7-hour studies. Four-hour groups included control (n… CONTINUE READING
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