Docosahexaenoic acid is required for the survival of rat retinal photoreceptors in vitro.

@article{Rotstein1996DocosahexaenoicAI,
  title={Docosahexaenoic acid is required for the survival of rat retinal photoreceptors in vitro.},
  author={Nora P Rotstein and Marta I. Avelda{\~n}o and Francisco J. Barrantes and Luis E Politi},
  journal={Journal of neurochemistry},
  year={1996},
  volume={66 5},
  pages={1851-9}
}
The effect of docosahexaenoic acid (DHA) on neuronal survival was studied in cultured cells isolated from newborn rat retina. In vivo, the content of DHA in the retina increased nearly fourfold from days 2 to 12 after birth, whereas in retinal cells in culture it remained constant. Unlike amacrine cells, the photoreceptor cells in control cultures underwent a selective degeneration, starting at day 7, that led to their massive death by day 11. The addition of DHA at day 7 led to its active… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

Similar Papers

Loading similar papers…