Docetaxel and gemcitabine combination in 133 advanced soft-tissue sarcomas: a retrospective analysis.

@article{Bay2006DocetaxelAG,
  title={Docetaxel and gemcitabine combination in 133 advanced soft-tissue sarcomas: a retrospective analysis.},
  author={J O Bay and Isabelle Laure Ray-Coquard and J{\'e}r{\^o}me Fayette and Serge Leyvraz and St{\'e}phane Cherix and S Piperno-neumann and Christine Chevreau and Nicolas Isambert and Etienne G C Brain and Georges Emile and Axel le Cesne and Angela Cioffi and Fabrice Kwiatkowski and J. M. Coindre and Nguyon Binh Bui and Fr{\'e}d{\'e}ric Peyrade and Nicolas Penel and J -Y Blay},
  journal={International journal of cancer},
  year={2006},
  volume={119 3},
  pages={706-11}
}
Advanced soft-tissue sarcomas are usually resistant to cytotoxic agents such as doxorubicin and ifosfamide. Antitumor activity has been observed for gemcitabine and docetaxel combination. We conducted a retrospective study on 133 patients (58 males/75 females) with unresectable or metastatic soft-tissue sarcoma. The median age at diagnosis was 51.7 (18-82), with 76 patients with leiomoyosarcoma and 57 patients with other histological subtypes. The initial localizations were limb (44), uterine… CONTINUE READING
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