Docetaxel: a tubulin-stabilizing agent approved for the management of several solid tumors.

@article{Ramaswamy2006DocetaxelAT,
  title={Docetaxel: a tubulin-stabilizing agent approved for the management of several solid tumors.},
  author={B Ramaswamy and Shannon L. Puhalla},
  journal={Drugs of today},
  year={2006},
  volume={42 4},
  pages={265-79}
}
Docetaxel is a semisynthetic taxane that acts by binding to the beta-tubulin subunit of the microtubules, resulting in cell-cycle arrest and apoptosis. It is approved for the management of early and advanced breast cancer, locally advanced and metastatic lung cancer and hormone refractory prostate cancer. Docetaxel has also shown significant antitumor… CONTINUE READING