Docetaxel, cisplatin, and fluorouracil; docetaxel and cisplatin; and epirubicin, cisplatin, and fluorouracil as systemic treatment for advanced gastric carcinoma: a randomized phase II trial of the Swiss Group for Clinical Cancer Research.

@article{Roth2007DocetaxelCA,
  title={Docetaxel, cisplatin, and fluorouracil; docetaxel and cisplatin; and epirubicin, cisplatin, and fluorouracil as systemic treatment for advanced gastric carcinoma: a randomized phase II trial of the Swiss Group for Clinical Cancer Research.},
  author={Arnaud D. Roth and Nicola Fazio and Kurt A. Jaeckle and Stephen C. Falk and Juerg Bernhard and Piercarlo Saletti and Dieter Koeberle and Markus M. Borner and Kaspar Rufibach and R Valdivia Maibach and Martin Wernli and Martin Leslie and Robert Glynne-Jones and Lukas A. Widmer and Matthew T. Seymour and Filippo Guglielmo Maria De Braud},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2007},
  volume={25 22},
  pages={
          3217-23
        }
}
PURPOSE This randomized phase II trial evaluated two docetaxel-based regimens to see which would be most promising according to overall response rate (ORR) for comparison in a phase III trial with epirubicin-cisplatin-fluorouracil (ECF) as first-line advanced gastric cancer therapy. PATIENTS AND METHODS Chemotherapy-naïve patients with measurable unresectable and/or metastatic gastric carcinoma, a performance status <or= 1, and adequate hematologic, hepatic, and renal function randomly… CONTINUE READING
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