Dobutamine “Stress” Test and Latent Cardiac Susceptibility to Inhaled Diesel Exhaust in Normal and Hypertensive Rats

@inproceedings{Hazari2012DobutamineT,
  title={Dobutamine “Stress” Test and Latent Cardiac Susceptibility to Inhaled Diesel Exhaust in Normal and Hypertensive Rats},
  author={Mehdi S Hazari and Justin Callaway and Darrell W. Winsett and Christina M. Lamb and Najwa Haykal-Coates and Quentin Todd Krantz and Charly J King and Daniel L. Costa and Aimen K. Farraj},
  booktitle={Environmental health perspectives},
  year={2012}
}
BACKGROUND Exercise "stress" testing is a screening tool used to determine the amount of stress for which the heart can compensate before developing abnormal rhythm or ischemia, particularly in susceptible persons. Although this approach has been used to assess risk in humans exposed to air pollution, it has never been applied to rodent studies. OBJECTIVE We hypothesized that a single exposure to diesel exhaust (DE) would increase the risk of adverse cardiac events such as arrhythmia and… CONTINUE READING
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