Dobutamine: ten years later.


Dobutamine is a commonly used positive inotrope for the short-term management of heart failure. It is commercially available as a 50:50 mixture of two isomers with unique effects on alpha- and beta adrenergic receptors. In dosages of 2-15 micrograms/kg/minute, dobutamine has been shown to increase cardiac output (mainly through stroke volume), reduce… (More)


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@article{Majerus1989DobutamineTY, title={Dobutamine: ten years later.}, author={Thomas C. Majerus and Joseph F. Dasta and Julie Bauman and Larry H. Danziger and Robert R. Ruffolo}, journal={Pharmacotherapy}, year={1989}, volume={9 4}, pages={245-59} }