Dobrava, but not Saaremaa, hantavirus is lethal and induces nitric oxide production in suckling mice.

@article{Klingstrm2006DobravaBN,
  title={Dobrava, but not Saaremaa, hantavirus is lethal and induces nitric oxide production in suckling mice.},
  author={Jonas Klingstr{\"o}m and Jonas Hardestam and {\AA}ke Lundkvist},
  journal={Microbes and infection},
  year={2006},
  volume={8 3},
  pages={
          728-37
        }
}
Hantaviruses are the causative agents of HFRS and HCPS (hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome), two severe, and often fatal human diseases. Mortality from HFRS varies between hantaviruses; Hantaan and Dobrava show the highest, Seoul intermediate, and Puumala low mortality. Saaremaa, genetically closely related to Dobrava, is also known to induce HFRS, with low or no mortality. In this study, mice were inoculated with Dobrava and Saaremaa viruses to test… CONTINUE READING
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