Do white matter changes contribute to the subsequent development of dementia in patients with mild cognitive impairment? A longitudinal study.

@article{Wolf2000DoWM,
  title={Do white matter changes contribute to the subsequent development of dementia in patients with mild cognitive impairment? A longitudinal study.},
  author={Henrike Wolf and G M Ecke and Simone Bettin and J. Kimball Dietrich and Hermann Josef Gertz},
  journal={International journal of geriatric psychiatry},
  year={2000},
  volume={15 9},
  pages={803-12}
}
OBJECTIVE White matter lesions on brain CT or MRI are a frequent finding in patients with Alzheimer's disease. However, little is known about the prognostic significance of these changes in cognitively impaired individuals who are at risk for subsequent development of dementia. This study aims at investigating the potential impact of white matter lucencies (WML) on brain CT on the course of mild cognitive impairment. PATIENTS AND METHODS Twenty-seven patients (mean age 72, SD 4.03) with mild… CONTINUE READING

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