• Corpus ID: 70994597

Do vitamins C and E affect respiratory infections

@inproceedings{Hemil2006DoVC,
  title={Do vitamins C and E affect respiratory infections},
  author={Harri Hemil{\"a}},
  year={2006}
}

Vitamin C and Exercise-induced Immunodepression [letter to the Editor] Pre-print Version of the Manuscript

TLDR
In a large cohort, it was found that the risk of the common cold and pneumonia were not reduced with moderate physical activity, refuting the universal validity of the " J "-model (Hemilä et al. 2003, 2006).

Vitamin C for preventing and treating the common cold.

TLDR
The failure of vitamin C supplementation to reduce the incidence of colds in the normal population indicates that routine mega-dose prophylaxis is not rationally justified for community use.

Bias against Vitamin C in Mainstream Medicine: Examples from Trials of Vitamin C for Infections

TLDR
This paper describes problems with two recent randomized trial reports published in JAMA which were presented in a way that misled readers, and considers potential explanations for the widespread bias against vitamin C.

Vitamin C and Infections

TLDR
The negative findings of some therapeutic common cold studies might be explained by the low doses of 3–4 g/day of vitamin C, so the effects of vitaminC against infections should be investigated further.

Vitamin C for preventing and treating tetanus.

TLDR
A single, non-randomised, poorly reported trial of vitamin C as a treatment for tetanus suggests a considerable reduction in mortality, however, concerns about trial quality mean that this result must be interpreted with caution and vitamin C cannot be recommended as a Treatment for Tetanus on the basis of this evidence.

Vitamin C and Community-acquired Pneumonia.

  • H. Hemilä
  • Medicine, Biology
    American journal of respiratory and critical care medicine
  • 2011
TLDR
The intrinsic PEEP likely greatly exceeded the extrinsic PEEP set on the ventilator, resulting in acute cor pulmonale, an important cause of death among patients treated with mechanical positive pressure ventilation.

Vitamin C for preventing and treating pneumonia.

TLDR
The current evidence is too weak to advocate widespread prophylactic use of vitamin C to prevent pneumonia in the general population, but therapeutic vitamin C supplementation may be reasonable for pneumonia patients who have low vitamin C plasma levels because its cost and risks are low.

Vitamin C and exercise-induced immunodepression

  • H. Hemilä
  • Medicine
    European Journal of Clinical Nutrition
  • 2007
TLDR
A systematic review of the role of nutrition on exercise-induced immunodepression found that further studies are required to provide unequivocal proof of effect by vitamin C, but the 50% effect calculated by Moreira is not novel and it is supported by three omitted trials.
...

References

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Clinical trials of homoeopathy.

TLDR
The evidence of clinical trials is positive but not sufficient to draw definitive conclusions because most trials are of low methodological quality and because of the unknown role of publication bias, which indicates that there is a legitimate case for further evaluation of homoeopathy, but only by means of well performed trials.

Winter illness and vitamin C: the effect of relatively low doses.

TLDR
There were no consistent or significant differences in the sickness experience of the subjects receiving the sustained-release vitamin capsules compared to those receiving the vitamin tablets, but subjects in both vitamin groups experienced less severe illness than subjects in the placebo group.

A critique of nutritional recommendations

TLDR
The Orthomolecular approach to medicine has been under constant criticism ever since its origin, but it is suggested that an even more important reason for the lack of acceptance results from the traditional conceptual approach towards nutrition.

Massive doses of vitamin C in the treatment of viral diseases.

  • W. L. Dalton
  • Medicine
    The Journal of the Indiana State Medical Association
  • 1962
TLDR
Klenner has advocated and employed massive doses of intravenous ascorbic acid for many years in the treatment of various viral diseases including measles, mumps, chickenpox, viral pneumonia and viral encephalitis and has reported remarkable results.

Some Pre-Lind Writers on Scurvy

To-day a few tenuous sentimental attachments have become for me very real ties to the University of Edinburgh. One is long interest in the history of scurvy, whose conquest you are commemorating. The
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