Do vasoregulatory mechanisms in exercising human muscle compensate for changes in arterial perfusion pressure?

@article{Walker2007DoVM,
  title={Do vasoregulatory mechanisms in exercising human muscle compensate for changes in arterial perfusion pressure?},
  author={Kathryn L Walker and Natasha Ruth Saunders and Dennis D Jensen and Jennifer L Kuk and Suzi-Lai Wong and Kyra E Pyke and Erin M Dwyer and Michael E Tschakovsky},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2007},
  volume={293 5},
  pages={H2928-36}
}
We tested the hypothesis that vasoregulatory mechanisms completely counteract the effects of sudden changes in arterial perfusion pressure on exercising muscle blood flow. Twelve healthy young subjects (7 female, 5 male) lay supine and performed rhythmic isometric handgrip contractions (2 s contraction/ 2 s relaxation 30% maximal voluntary contraction). Forearm blood flow (FBF; echo and Doppler ultrasound), mean arterial blood pressure (arterial tonometry), and heart rate (ECG) were measured… CONTINUE READING