Do the dimensions of the temperament and character inventory map a simple genetic architecture? Evidence from molecular genetics and factor analysis.

@article{Herbst2000DoTD,
  title={Do the dimensions of the temperament and character inventory map a simple genetic architecture? Evidence from molecular genetics and factor analysis.},
  author={Jeffrey H Herbst and Alan B. Zonderman and Robert R Mccrae and Paul T Costa},
  journal={The American journal of psychiatry},
  year={2000},
  volume={157 8},
  pages={1285-90}
}
OBJECTIVE It has been reported that the human temperament dimensions of novelty seeking and harm avoidance are associated with polymorphisms in the D(4) dopamine receptor gene (D4DR) and the serotonin-transporter-linked promoter region (5-HTTLPR), respectively. Although these findings are consistent with Cloninger's hypothesized psychobiological model of… CONTINUE READING