Do serum biomarkers really measure breast cancer?

  title={Do serum biomarkers really measure breast cancer?},
  author={Jonathan L. Jesneck and Sayan Mukherjee and Zoya R. Yurkovetsky and Merlise A. Clyde and Jeffrey R. Marks and Anna E. Lokshin and Joseph Y. Lo},
  booktitle={BMC Cancer},
Because screening mammography for breast cancer is less effective for premenopausal women, we investigated the feasibility of a diagnostic blood test using serum proteins. This study used a set of 98 serum proteins and chose diagnostically relevant subsets via various feature-selection techniques. Because of significant noise in the data set, we applied iterated Bayesian model averaging to account for model selection uncertainty and to improve generalization performance. We assessed… CONTINUE READING
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