Do schizoaffective disorders exist at all?

@article{Maier2006DoSD,
  title={Do schizoaffective disorders exist at all?},
  author={Wolfgang Maier},
  journal={Acta Psychiatrica Scandinavica},
  year={2006},
  volume={113}
}
  • W. Maier
  • Published 1 May 2006
  • Psychology, Medicine
  • Acta Psychiatrica Scandinavica
More than 100 years ago Kraepelin proposed a very practical and persuasive solution to a longstanding problem in clinical psychiatry. He proposed to reduce heterogeneity by splitting the perplexing variety of psychopathological signs and symptoms, of patterns of deviant behavior and experiences, of shortand long-term course and outcome of functional disturbances into two major groups: schizophrenia (dementia praecox) and affective disorders (manic-depressive illness) (1). In this way, he… 
Do schizoaffective disorders exist at all?
  • A. Marneros
  • Psychology, Medicine
    Acta psychiatrica Scandinavica
  • 2007
In the Editorial of the May 2006 issue of Acta Psychiatrica Scandinavica (1), Prof. Maier gives his answer to the above question. The question is very old, the answer is not very new. In the last 100
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Schizoaffective disorder, initiated in 1933, challenged the "Kraepelinian dichotomy" and Bleuler's contention that psychosis defined schizophrenia. Schizoaffective disorder recognized the diagnosti...
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Evidence for separate diseases?
TLDR
Depression does not represent comorbidity, but an integral part of psychosis, and a dimensional disease model based on successively emerging hierarchical symptom patterns is offered as an explanation.
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TLDR
A good social and industrial adjustment, the presence of a definite and specific environmental stress, the interest in life and its opportunities, and the absence of any passivity or withdrawal are some of the factors favoring recovery.
Reliability and validity of the DSM-IV diagnostic category of schizoaffective disorder: preliminary data.
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The findings support the need for a longitudinally based diagnostic process in incidence samples and changes in diagnosis, particularly to schizophrenia, are mostly attributable to the evolution of the illness.
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The findings suggest neuroleptics are unlikely to be the major cause of depressions in patients suffering from acute schizophrenic or paranoid psychoses, and the frequency and intensity of depression decreased from admission to discharge.
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Patients with psychoses often suffer from affective symptoms and the reliability of the clinical use of the schizoaffective disorder diagnosis in university settings is examined.
Schizophrenia and bipolar disorder: differences and overlaps
TLDR
The diagnostic split between schizophrenia and bipolar disorder is unable to define distinct etiological and/or pathophysiological entities.
Ten-year outcome: patients with schizoaffective disorders, schizophrenia, affective disorders and mood-incongruent psychotic symptoms
TLDR
Schizoaffective outcome was better than schizophrenic outcome and poorer than outcome for psychotic affective disorders, and Mood-incongruent psychotic symptoms have negative prognostic implications.
Family history of psychiatric illness as a risk factor for schizoaffective disorder: a Danish register-based cohort study.
TLDR
Schizoaffective disorder is not simply a subgroup of either bipolar disorder or schizophrenia but may be genetically linked to both, with schizoaffection being a subtype of each or a genetic intermediate form.
A twin study of genetic relationships between psychotic symptoms.
TLDR
If diagnostic hierarchies are relaxed, there is a degree of overlap in the genes contributing to RDC schizophrenic, schizoaffective, and manic syndromes, and Supplementing the traditional approach of assigning a single main lifetime diagnosis with information on within-person comorbidity of psychotic syndrome may provide valuable information about the familial aggregation of psychotic symptoms.
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