Do reactive oxygen species underlie the mechanism of apoptosis in the tadpole tail?

@article{Hanada1997DoRO,
  title={Do reactive oxygen species underlie the mechanism of apoptosis in the tadpole tail?},
  author={Hideki Hanada and Akihiko Kashiwagi and Yoshiki Takehara and Tomoko Kanno and Masanori Yabuki and Junzo Sasaki and Masayasu Inoue and Kozo Utsumi},
  journal={Free radical biology & medicine},
  year={1997},
  volume={23 2},
  pages={
          294-301
        }
}
Although "programmed cell death" has been postulated to underlie the mechanism for the disappearance of the tadpole tail, critical factors that trigger this phenomenon remain to be elucidated. To investigate the mechanism for the disappearance of the tail, changes in morphology, DNA status and the enzymes which metabolize reactive oxygen species were determined in the tail of Rana rugosa tadpoles. Histological examination revealed that apoptotic cell death was apparent in the tail myocytes… CONTINUE READING

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