Do radiographic joint damage and disease activity influence functional disability through different mechanisms? Direct and indirect effects of disease activity in established rheumatoid arthritis.

Abstract

OBJECTIVE To explore the relationship between rheumatoid arthritis (RA) disease activity and functional disability over time, considering indirect (predictive) and direct (concurrent) associations as well as the influence of radiographic joint damage and treatment strategy. METHODS Functional disability [Health Assessment Questionnaire (HAQ)], disease… (More)
DOI: 10.3899/jrheum.121346

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