Do protein-protein interaction databases identify moonlighting proteins?

@article{Gmez2011DoPI,
  title={Do protein-protein interaction databases identify moonlighting proteins?},
  author={Antonio Bermejo G{\'o}mez and Sergio Barroso Hern{\'a}ndez and Isaac Amela and Jaume Pi{\~n}ol and Juan Cedano and Enrique Querol},
  journal={Molecular bioSystems},
  year={2011},
  volume={7 8},
  pages={2379-82}
}
One of the most striking results of the human (and mammalian) genomes is the low number of protein-coding genes. To-date, the main molecular mechanism to increase the number of different protein isoforms and functions is alternative splicing. However, a less-known way to increase the number of protein functions is the existence of multifunctional, multitask, or "moonlighting", proteins. By and large, moonlighting proteins are experimentally disclosed by serendipity. Proteomics is becoming one… CONTINUE READING

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To - date , the main molecular mechanism to increase the number of different protein isoforms and functions is alternative splicing .
To - date , the main molecular mechanism to increase the number of different protein isoforms and functions is alternative splicing .
To - date , the main molecular mechanism to increase the number of different protein isoforms and functions is alternative splicing .
To - date , the main molecular mechanism to increase the number of different protein isoforms and functions is alternative splicing .
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