Do organic solvents induce changes in the dopaminergic system? Positron emission tomography studies of occupationally exposed subjects.

@article{Edling1997DoOS,
  title={Do organic solvents induce changes in the dopaminergic system? Positron emission tomography studies of occupationally exposed subjects.},
  author={Christer Edling and B H Hellman and Bj{\"o}rn Arvidson and Jan Olof Andersson and Per Hartvig and Anders Lilja and Sven Valind and Bengt L{\aa}ngstr{\"o}m},
  journal={International archives of occupational and environmental health},
  year={1997},
  volume={70 3},
  pages={
          180-6
        }
}
OBJECTIVES The objective of this study was to test the hypothesis that long-term occupational exposure to organic solvents may effect the levels and turnover of dopamine in man. METHODS A study was performed on 17 patients with neuropsychiatric symptoms due to occupational solvent exposure, and 11 healthy non-exposed male volunteers (controls). Positron emission tomography (PET) was used to assess striatal dopaminergic function, using L-[11C]DOPA, [11C]nomifensine and [11C]raclopride as… CONTINUE READING

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