Do-not-resuscitate orders in trauma patients may bias mortality-based effect estimates: An evaluation using the PROMMTT study

  title={Do-not-resuscitate orders in trauma patients may bias mortality-based effect estimates: An evaluation using the PROMMTT study},
  author={C. Wade and D. D. del Junco and E. Fox and B. Cotton and M. Cohen and P. Muskat and M. Schreiber and M. Rahbar and R. M. Sauer and K. Brasel and E. Bulger and J. Myers and H. Phelan and L. Alarcon and J. Holcomb},
  journal={Journal of Trauma and Acute Care Surgery},
  • C. Wade, D. D. del Junco, +12 authors J. Holcomb
  • Published 2013
  • Medicine
  • Journal of Trauma and Acute Care Surgery
  • BACKGROUND The impact of do-not-resuscitate (DNR) orders has not been systematically evaluated in acute trauma research. We determined the frequency, timing, and impact on mortality-based effect estimates for patients with DNR orders in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study. METHODS Trauma patients surviving at least 30 minutes and transfused one or greater unit of red blood cell within 6 hours of admission (n = 1,245) from 10 Level 1 centers were… CONTINUE READING
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