Do neuron-specific enolase levels discriminate between small-cell lung cancer and mediastinal tumors?

@article{Ebert1996DoNE,
  title={Do neuron-specific enolase levels discriminate between small-cell lung cancer and mediastinal tumors?},
  author={Werner Ebert and Roland Ryll and Thomas Muley and George Edward Hug and Peter Drings},
  journal={Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine},
  year={1996},
  volume={17 6},
  pages={362-8}
}
The capacity of pretherapeutically assessed neuron-specific enolase (NSE) to differentiate between small cell lung cancer (SCLC) and mediastinal tumors was investigated retrospectively in a series of 320 patients. NSE was found to be increased in 95/130 (73.1%) patients with SCLC, in 4/62 (6.5%) patients with Hodgkin's disease, in 10/58 (17.2%) patients with non-Hodgkin's lymphoma, in 5/16 (31.3%) patients with teratoma, and in 6/54 (11.1%) patients with thymoma. The cut-off value, defined as… CONTINUE READING