Do microtubules around the Toxoplasma gondii-containing parasitophorous vacuole in skeletal muscle cells form a barrier for the phagolysosomal fusion?

@article{Andrade2001DoMA,
  title={Do microtubules around the Toxoplasma gondii-containing parasitophorous vacuole in skeletal muscle cells form a barrier for the phagolysosomal fusion?},
  author={Elisabete Ferreira de Andrade and Ana Carolina Stumbo and Luiz Henrique Monteiro-Leal and Lucas de Lima Carvalho and Helene S Barbosa},
  journal={Journal of submicroscopic cytology and pathology},
  year={2001},
  volume={33 3},
  pages={337-41}
}
The intracellular fate of Toxoplasma gondii was studied in primary cultures of skeletal muscle cells (SMC). The labelling of secondary lysosomes with BSA-Au particles showed no phagolysosomal fusion with the vacuole containing the parasite. After internalization of the parasites, the parasitophorous vacuole became involved by closely apposed endoplasmic reticulum (ER) and mitochondria; within 18 h of interaction, microtubules were visualized in association with the parasitophorous vacuole… CONTINUE READING

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