Do microsatellites reflect genome-wide genetic diversity in natural populations? A comment on Väli et al. (2008).

@article{Ljungqvist2010DoMR,
  title={Do microsatellites reflect genome-wide genetic diversity in natural populations? A comment on V{\"a}li et al. (2008).},
  author={Marcus Ljungqvist and Mikael {\AA}kesson and Bengt Hansson},
  journal={Molecular ecology},
  year={2010},
  volume={19 5},
  pages={
          851-5
        }
}
A recent study by Väli et al. (2008) highlights that microsatellites will often provide a poor prediction of the genome-wide nucleotide diversity of wild populations, but does not fully explain why. To clarify and stress the importance of identity disequilibrium and marker variability for correlations between multilocus heterozygosity and genome-wide genetic variability, we performed a simple simulation with different types of markers, corresponding to microsatellites and SNPs, in populations… CONTINUE READING
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