Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways?

@article{Coleman2002DoLA,
  title={Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways?},
  author={Rosalind A Coleman and Tal M. Lewin and Cynthia G Van Horn and Maria R Gonzalez-Baro},
  journal={The Journal of nutrition},
  year={2002},
  volume={132 8},
  pages={2123-6}
}
Recent studies suggest that the long-chain acyl-CoA synthetases (ACS) may play a role in channeling fatty acids either toward complex lipid synthesis and storage or toward oxidation. Each of the five members of the ACS family that has been cloned has a distinct tissue distribution and subcellular location, and is regulated independently during cellular differentiation and by diverse hormones and nuclear transcription factors including adrenocorticotropic hormone (ACTH), peroxisomal proliferator… CONTINUE READING

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