Do inhaled corticosteroids affect perception of dyspnea during bronchoconstriction in asthma?

@article{Ottanelli2001DoIC,
  title={Do inhaled corticosteroids affect perception of dyspnea during bronchoconstriction in asthma?},
  author={R. Ottanelli and Elisabetta Rosi and Isabella Romagnoli and M. Grazzini and Loredana Stendardi and Roberto Duranti and Giorgio Scano},
  journal={Chest},
  year={2001},
  volume={120 3},
  pages={
          770-7
        }
}
BACKGROUND Some of the disagreements on the perception of dyspnea (PD) during bronchoconstriction in asthma patients could depend on the interrelationships among the following: (1) the influence of baseline airflow obstruction on the patient's ability to detect any further increase in airway resistance; (2) the effect of eosinophilic inflammation on the airway; (3) bronchial hyperresponsiveness (BHR); and (4) the effect of inhaled corticosteroids (ICSs). OBJECTIVE We hypothesized that if the… 
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Perception of dyspnea during acetylcholine-induced bronchoconstriction in asthmatic children.
Dyspnea, respiratory function and sputum profile in asthmatic patients during exacerbations.
TLDR
In acute asthmatic patients, dyspnea measurement, functional measurements and sputum analysis may be useful in monitoring disease activity, response to therapy and can provide different information on the state of the disease.
Dyspnea Perception and Reversibility of Methacholine-Induced Unlimited Airway Narrowing in Asthmatics
TLDR
Asthmatics during methacholine-induced unlimited airway narrowing exhibit diminished perception of dyspnea and lower bronchial reversibility to the baseline 20 minutes after inhalation of salbutamol, suggesting that more careful monitoring of the lung function for timely recognition of asthma deteriorations and adequate bronchodilatory therapy during severe acute attacks should be recommended for such patients.
Dynamic hyperinflation during bronchoconstriction in asthma: implications for symptom perception.
TLDR
Four dominant qualities of dyspnea in asthma (inspiratory difficulty, chest tightness, unsatisfied inspiration, and work) were reported early in the course of MCT and evolved in parallel, becoming more prevalent at maximum response.
The influence of corticosteroids on the perception of dyspnea in asthma.
Measures of Perception of Bronchoconstriction and Clinical and Functional Data Are Not Interrelated in Asthma
TLDR
Irrespective of the scale employed, the data indicate the need for directly assessing PB rather than deriving it from clinical and functional data and level of BHR, which is of questionable clinical significance.
Dyspnea and asthma
TLDR
Dyspnea – the perception of respiratory discomfort – is a primary symptom of asthma and possible ways to link mechanisms, measurement and treatment that will increase the understanding of this condition are examined.
Perception of Airway Obstruction and Airway Inflammation in Asthma: A Review
TLDR
It is concluded that regardless of whether mechanical or chemical inflammatory factors are involved, much variability in dyspnea scores remains unexplained.
Effect of adjunct fluticasone propionate on airway physiology during rest and exercise in COPD.
Physiological effects of roflumilast at rest and during exercise in COPD
TLDR
Roflumilast treatment was associated with progressive improvement of airway function but not lung hyperinflation, and newly described non-bronchodilator effects of roflumilaston included small but consistent improvements in air trapping and Sp,O2 during exercise.
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