Do early-life events permanently alter behavioral and hormonal responses to stressors?

@article{Anisman1998DoEE,
  title={Do early-life events permanently alter behavioral and hormonal responses to stressors?},
  author={Hymie Anisman and Marilee D. Zaharia and Michael J. Meaney and Zul Merali},
  journal={International Journal of Developmental Neuroscience},
  year={1998},
  volume={16},
  pages={149-164}
}
Early-life stimulation (e.g., brief handling) attenuates the behavioral and neuroendocrine responses to stressors encountered in adulthood, particularly with respect to activation of hypothalamic-pituitary-adrenal (HPA) activity. In contrast, if neonates were subjected to a more severe stressor, such as protracted separation from the dam or exposure to an endotoxin, then the adult response to a stressor was exaggerated. These early-life experiences program HPA functioning, including negative… CONTINUE READING
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