Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy?

@article{Fayda2015DoCL,
  title={Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy?},
  author={Merdan Fayda and Mustafa Isin and Makbule Tambaş and Murat Emin Guveli and Rasim Meral and M. Erkan Altun and Dilek Uygur Şahin and Gozde Ozkan and Yasemin Şanli and Husniye Isin and Esra {\"O}zg{\"u}r and Uğur Gezer},
  journal={Tumor Biology},
  year={2015},
  volume={37},
  pages={3969-3978}
}
Long non-coding RNAs (lncRNAs) have been shown to be aberrantly expressed in head and neck cancer (HNC). The aim of the present study was to evaluate plasma levels of three lncRNA molecules (lincRNA-p21, GAS5, and HOTAIR) in the treatment response in HNC patients treated with radical chemoradiotherapy (CRT). Forty-one patients with HNC were enrolled in the study. Most of the patients had nasopharyngeal carcinoma (n = 27, 65.9 %) and locally advanced disease. Blood was drawn at baseline and… CONTINUE READING
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