Do chemo- and radiotherapy affect the DNA repair ability of lymphocytes?

@article{Kovacs1992DoCA,
  title={Do chemo- and radiotherapy affect the DNA repair ability of lymphocytes?},
  author={Eva Kovacs and Helen Langemann and H. -G. Ludwig},
  journal={Archives of Gynecology and Obstetrics},
  year={1992},
  volume={251},
  pages={121-126}
}
The DNA repair ability of unstimulated lymphocytes damaged by ultraviolet irradiation was measured in a group of 15 breast cancer patients before surgery, and 3 to 5 years later a) after surgery alone (n=6), or b) after surgery with additional chemo- and/or radiotherapy (n=9). In group a) 3 out of 6 patients had reduced repair before and 2 out of 6 after surgery. In the group b) 4 out of 9 patients had reduced repair before surgery, and 9 out of 9 after surgery plus chemo/radiotherapy. These… CONTINUE READING

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The relationship between DNA repair after alkylation damage and in vitro aging in human T-lymphocytes

  • JN Hartshorn, SH Robinson
  • Mutat Res
  • 1990
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