Mechanistic aspects of carotenoid biosynthesis.
- Chemistry, BiologyChemical reviews
Carotenoids represent a large class of terpenoids characterized by an extensively conjugated polyene chain that carries out light independent functions in scavenging peroxyl radicals and preventing oxidative damage particularly against singlet oxygen (1O2).
Interactions of dietary carotenoids with activated (singlet) oxygen and free radicals: potential effects for human health.
- ChemistryMolecular nutrition & food research
These reactions are related to CAR redox potentials with LYC being the lowest (most easily oxidised) allowing LYC to reduce/repair all other CAR radical cations and LYC 'sacrificed' where mixtures of CARs are present in oxidative environments.
Pro-oxidant Actions of Carotenoids in Triggering Apoptosis of Cancer Cells: A Review of Emerging Evidence
- Biology, ChemistryAntioxidants
This review discusses possible mechanisms of carotenoid-triggered ROS production in cancer cells, the activation of pro-apoptotic signaling by ROS, and apoptotic cell death, and synergistic actions ofcarotenoids with ROS-inducing anti-cancer drugs are discussed, and research gaps are suggested.
Carotenoid accumulation affects redox status, starch metabolism, and flavonoid/anthocyanin accumulation in citrus
- Biology, MedicineBMC Plant Biology
In citrus, altered carotenoid accumulation resulted in dramatic effects on metabolic processes involved in redox modification, starch degradation, and flavonoid/anthocyanin biosynthesis.
Expression of a Chromoplast-Specific Lycopene β-Cyclase Gene (CYC-B) Is Implicated in Carotenoid Accumulation and Coloration in the Loquat
- Medicine, BiologyBiomolecules
Direct evidences that CYC-B gene is involved in carotenoid accumulation and coloration in the loquat are provided.
A cytochrome P450 superfamily gene, IbCYP82D47, increases carotenoid contents in transgenic sweet potato.
- MedicinePlant science : an international journal of experimental plant biology
Genome-wide identification and expression profiling of the carotenoid cleavage dioxygenase (CCD) gene family in Brassica napus L
- Biology, MedicinePloS one
Carotenoid cleavage dioxygenase (CCD), a key enzyme in carotenoid metabolism, cleaves carotenoids to form apo-carotenoids, which play a major role in plant growth and stress responses. CCD genes had…
Down-regulation of β-carotene hydroxylase increases β-carotene and total carotenoids enhancing salt stress tolerance in transgenic cultured cells of sweetpotato.
- Biology, MedicinePhytochemistry
Plant Antioxidants Affect Human and Gut Health, and Their Biosynthesis Is Influenced by Environment and Reactive Oxygen Species
Many environmental stresses cause an increase in reactive oxygen species in plants and alter their nutritional value. Plants respond to many stresses by producing increased amounts of compounds with…
Cloning and Prokaryotic Expression of Carotenoid Cleavage Dioxygenases from Mulberry (Morus notabilis)
- MedicineEvidence-based complementary and alternative medicine : eCAM
In this paper, six CCD genes were obtained from Morus notabilis by reverse transcription-polymerase chain reaction (RT-PCR) and they were classified into three subgroups based on gene structures and phylogenetic analysis.
SHOWING 1-10 OF 39 REFERENCES
Carotenoids as modulators of lipid membrane physical properties.
- ChemistryBiochimica et biophysica acta
Antioxidant and prooxidant properties of carotenoids.
- ChemistryArchives of biochemistry and biophysics
It is unlikely that carotenoids actually act as prooxidants in biological systems; rather they exhibit a tendency to lose their effectiveness as antioxidants.
Singlet oxygen quenching by dietary carotenoids in a model membrane environment.
- ChemistryArchives of biochemistry and biophysics
Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids.
- Chemistry, BiologyTrends in plant science
Carotene oxygenases: a new family of double bond cleavage enzymes.
- BiologyThe Journal of nutrition
The results suggest that the source of vitamin A originates from carotenoids in the corresponding tissues, in addition to retinol supplied from liver stores.
The role of carotenoids in the prevention of human pathologies.
- BiologyBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Relative One-Electron Reduction Potentials of Carotenoid Radical Cations and the Interactions of Carotenoids with the Vitamin E Radical Cation
Pulse radiolysis studies have been used to determine the electron-transfer rate constants between various pairs of carotenoids, one of which is present as the radical cation. These dietary…
Antioxidant Properties of Carotenoids In Vitro and In Vivo
Abstract Carotenoids are a class of natural pigments familiar to all through the orange–red to yellow colors of many fruits, vegetables, and flowers, as well as for the provitamin A activity that…
Lutein and zeaxanthin as protectors of lipid membranes against oxidative damage: the structural aspects.
- BiologyArchives of biochemistry and biophysics
A protective effect of lutein and zeaxanthin against oxidative damage of egg yolk lecithin liposomal membranes induced by exposure to UV radiation and incubation with 2, 2'-azobis(2-methypropionamidine)dihydrochloride, a water-soluble peroxidation initiator, was studied.