Do antiepileptic drugs increase the risk of suicidality in adult patients with epilepsy?: a critically appraised topic.


BACKGROUND The US Food and Drug Administration (FDA) released an alert in 2008 regarding an increased risk of suicidality in patients taking antiepileptic drugs (AEDs). The analysis that prompted this blanket warning has since been criticized for multiple flaws, and its relevance to patients with epilepsy is unclear. OBJECTIVE To critically assess current… (More)
DOI: 10.1097/NRL.0b013e3181f79f37