Do antidepressants cause suicidality in children? A Bayesian meta-analysis

@article{Kaizar2006DoAC,
  title={Do antidepressants cause suicidality in children? A Bayesian meta-analysis},
  author={Eloise E Kaizar and Joel B Greenhouse and Howard J. Seltman and Kelly J. Kelleher},
  journal={Clinical Trials},
  year={2006},
  volume={3},
  pages={73 - 98}
}
Background To quantify the risk of suicidal behavior/ideation (suicidality) for children who use antidepressants, the FDA collected randomized placebo-controlled trials of antidepressant efficacy in children. Although none of the 4487 children completed suicide, 1.7% exhibited suicidality. The FDA meta-analyzed these studies and found sufficient evidence of an increased risk to require a black-box warning on antidepressants for children. Purpose The FDA considered different drug formulations… Expand
Antidepressants use in pediatric populations
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Safety warnings about antidepressants and widespread media coverage decreased antidepressant use, and there were simultaneous increases in suicide attempts among young people. Expand
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