Do antidepressants cause suicidality in children? A Bayesian meta-analysis

  title={Do antidepressants cause suicidality in children? A Bayesian meta-analysis},
  author={Eloise E Kaizar and J. Greenhouse and H. Seltman and K. Kelleher},
  journal={Clinical Trials},
  pages={73 - 98}
  • Eloise E Kaizar, J. Greenhouse, +1 author K. Kelleher
  • Published 2006
  • Medicine
  • Clinical Trials
  • Background To quantify the risk of suicidal behavior/ideation (suicidality) for children who use antidepressants, the FDA collected randomized placebo-controlled trials of antidepressant efficacy in children. Although none of the 4487 children completed suicide, 1.7% exhibited suicidality. The FDA meta-analyzed these studies and found sufficient evidence of an increased risk to require a black-box warning on antidepressants for children. Purpose The FDA considered different drug formulations… CONTINUE READING
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