Do Selective Serotonin Reuptake Inhibitors (SSRIs) Cause Fractures?

@article{Warden2016DoSS,
  title={Do Selective Serotonin Reuptake Inhibitors (SSRIs) Cause Fractures?},
  author={S. Warden and R. Fuchs},
  journal={Current Osteoporosis Reports},
  year={2016},
  volume={14},
  pages={211-218}
}
  • S. Warden, R. Fuchs
  • Published 2016
  • Medicine
  • Current Osteoporosis Reports
  • Recent meta-analyses report a 70 % increase in fracture risk in selective serotonin reuptake inhibitor (SSRI) users compared to non-users; however, included studies were observational and limited in their ability to establish causality. Here, we use the Bradford Hill criteria to explore causality between SSRIs and fractures. We found a strong, consistent, and temporal relationship between SSRIs and fractures, which appears to follow a biological gradient. However, specificity and biological… CONTINUE READING

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