Do Proton Pump Inhibitors Decrease Calcium Absorption?

@inproceedings{Hansen2010DoPP,
  title={Do Proton Pump Inhibitors Decrease Calcium Absorption?},
  author={Karen E. Hansen and A. Noel Jones and Mary J. Lindstrom and Lisa A Davis and Toni E Ziegler and Kristina L Penniston and Amy L. Alvig and Martin M. Shafer},
  booktitle={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2010}
}
Proton pump inhibitors (PPIs) increase osteoporotic fracture risk presumably via hypochlorhydria and consequent reduced fractional calcium absorption (FCA). Existing studies provide conflicting information regarding the direct effects of PPIs on FCA. We evaluated the effect of PPI therapy on FCA. We recruited women at least 5 years past menopause who were not taking acid suppressants. Participants underwent three 24-hour inpatient FCA studies using the dual stable isotope method. Two FCA… CONTINUE READING
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