Do Pancreatic β Cells “Taste” Nutrients to Secrete Insulin?

@article{Henquin2012DoP,
  title={Do Pancreatic $\beta$ Cells “Taste” Nutrients to Secrete Insulin?},
  author={Jean-Claude Henquin},
  journal={Science Signaling},
  year={2012},
  volume={5},
  pages={pe36 - pe36}
}
  • J. Henquin
  • Published 2012
  • Biology, Medicine
  • Science Signaling
The role of β cell taste receptors in the control of insulin secretion is unclear. Insulin secretion from pancreatic β cells is controlled by nutrients, hormones, and neurotransmitters. Unlike the latter, which work through classic receptors, glucose and most other nutrients do not interact with membrane receptors but must be metabolized by β cells to induce insulin secretion. Studies have revealed the presence of umami and sweet taste receptors and their downstream effectors in β cells. That… Expand
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