Do Leukotrienes (lt) Control Pulmonary Blood Flow (pbf) in the Fetal Lamd?

Abstract

Pulmonary vascular resistance (PVR) is elevated in the fetus to maintain a low PBF. Lipooxygenase products of arachadonic acid metabolism, including LTC4 and LTD4, are potent pulmonary vasoconstrictors in adult animals. To evaluate whether LT contributes to the control of PVR and PBF in fetuses, the effects of LT inhibition were studied in 7 chronically… (More)
DOI: 10.1203/00006450-198404001-01526

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics